Chelation works by removing toxins such as heavy metals like lead, mercury and unwanted calcium from most organs in the body. Newly discovered cause of 85% of major heart attacks is due to plaque in the blood vessels in half of the males over 40 years of age in United States. Unwanted calcium causes a build up of plaque, hardening of the arteries, thus causing potential heart problems. The calcium in the plaque is removed and put into water-soluble complexes (chelates) which can be readily excreted through the kidneys. Clinical observations reveal that the amount of calcium in bones is not affected by the removal of calcium in the arteries nor is it diminished by the use of EDTA chelation therapy. 螯合作用通過去除體內大多數器官中的鉛，汞和不需要的鈣等重金屬的毒素來起作用。不需要的鈣會導致斑塊積聚，動脈硬化，從而引起潛在的心臟問題。最新發現、一半美國40歲以上男性主要心髒病發作的原因是由於血管中有斑塊。去除粥樣斑塊中的鈣並將其放入水溶性複合物（螯合物）中，便可以容易地通過腎臟排泄。臨床觀察表明，骨骼中鈣的含量不受動脈中鈣的去除影響，也不會因使用EDTA螯合療法而減少。

Chelation therapy (using EDTA) has been a standard treatment for lead and heavy metal poisoning since World War II. In the 1940's and 1950's, patients taking EDTA chelation therapy for lead poisoning reported improved memory, vision, hearing and smell, and diminished leg and heart pain. Since then nearly 1,000,000 patients with cardiovascular disease have been treated successfully. Further, EDTA has been used as a food additive for over 30 years. 自第二次世界大戰以來，螯合療法（使用EDTA）一直是鉛和重金屬中毒的標準治療方法。在20世紀40年代和50年代，使用EDTA螯合療法治療鉛中毒的患者報告記憶力，視力，聽覺和嗅覺均有改善，腿部和心臟疼痛減輕。從那時起，已有近1,000,000名心血管疾病患者得到了成功治療。此外，EDTA用作食品添加劑已超過30年。

Ethylenediaminetetraacetic acid (EDTA) is produced as several salts, notably disodium EDTA, calcium disodium EDTA, and tetrasodium EDTA (typically as the hydrate). A specific salt of EDTA, known as sodium calcium edetate, is used to bind metal ions in the practice of chelation therapy, such as for treating mercury and lead poisoning. It is used in a similar manner to remove excess iron from the body. This therapy is used to treat the complication of repeated blood transfusions, as would be applied to treat thalassaemia. 乙二胺四乙酸（EDTA）是以幾種鹽的形式生產，特別是EDTA二鈉，EDTA鈣二鈉和EDTA四鈉（通常為水合物）。乙二胺四乙酸的另一種特殊鹽，稱為乙二胺四乙酸鈣鈉，在螯合療法的實踐中用於結合金屬離子，用於治療汞和鉛中毒。亦可清除體內多餘的鐵。該療法亦用於治療反复輸血的並發症，及治療地中海貧血。

In almost 30 years of comparative case studies, researchers have discovered that IV EDTA chelation therapy, especially when augmented by scientifically formulated nutritive support, improves the functioning of most organs. A completed National Institute of Health (NIH) funded study in 2011 (in collaboration with American College for Advancement in Medicine (ACAM) [1] : Trial to Assess Chelation Therapy [TACT]), was published in the Journal of American Medicine (JAMA) by Lamas et al, March 23, 2013. The study showed the practice to be of moderate benefit to heart-attack survivors. A subgroup data showed an even more robust protective effect of chelation, specifically for post-myocardial infarction patients with diabetes. Researchers reported a 51 percent reduction in cardiovascular risk in the subgroup of persons with diabetes in the treatment arm that received chelation plus vitamins versus persons with diabetes treated with placebo(2). 美國國立衛生研究院（National Institute of Health）於2011年資助的一項研究（評估螯合療法的臨床驗証 [Trial to Assess Chelation Therapy]）在2013年3月美國醫學雜誌（Journal of American Medical Association）上發表螯合療法對心髒病發作的倖存者頗有價值。亞組數據顯示螯合作用更具有強的保護作用，特別是對於糖尿病後心肌梗塞患者。研究人員報告說，接受螯合加維生素治療的糖尿病患者的心血管風險相對安慰劑治療的糖尿病患者降低51％ 此外，在近30年 臨床比較案例研究中，研究人員發現静脈注射EDTA螯合療法，特別在通過科學配方的營養素增強下，可以改善大多數器官的功能

Improves circulatory disorders such as coronary artery disease (CAD), cerebrovascular disease, or peripheral vascular disease; detoxifies the body of heavy metals such as lead, cadmium, and mercury; and combats degenerative diseases and slows the aging process. 改善冠狀動脈疾病（Coronary Artery Disease），腦血管疾病或外周血管疾病等循環系統疾病; 解除身體的重金屬，如鉛，鎘和汞; 並對抗退化性疾病及減緩衰老過程。

Patients recline in a chair in the clinician’s office for one to four hours once to three times weekly for a series of 20 to 80 chelations, depending on medical condition treated. “Booster” chelations may be administered on a monthly basis or intermittently for years. 根據所治療的病情，可20至40次不等。一個療程需時一到四個小時，每週一次至三次。治療后、可以定期每月或間歇加強螯合劑。